Arg25Pro polymorphism of transforming growth factor-beta1 and its role in the pathogenesis of essential hypertension in Russian population of the Central Chernozem Region

Arg25Pro polymorphism of transforming growth factor-beta1 and its role in the pathogenesis of essential hypertension in Russian population of the Central Chernozem Region

We studied the relationship between Arg25Pro polymorphism of TGFbeta1 gene and predisposition to essential hypertension in the Russian population of Central Chernozem Region (n=402). An association was found between 25Pro allele and 25ArgPro genotype with low risk of essential hypertension in male i...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Bulletin of experimental biology and medicine 2007-07, Vol.144 (1), p.66-68
Hauptverfasser: Ivanov, V P, Solodilova, M A, Polonnikov, A V, Belugin, D A, Shestakov, A M, Ushachev, D V, Khoroshaya, I V, Katargina, L N, Kozhukhov, M A, Kolesnikova, O E
Format: Artikel
Sprache:eng ; rus
Schlagworte:
Female
Gene Frequency
Genotype
Humans
Hypertension - genetics
Male
Polymorphism, Genetic
Russia
Transforming Growth Factor beta1 - genetics
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:We studied the relationship between Arg25Pro polymorphism of TGFbeta1 gene and predisposition to essential hypertension in the Russian population of Central Chernozem Region (n=402). An association was found between 25Pro allele and 25ArgPro genotype with low risk of essential hypertension in male individuals.
ISSN:0007-4888