Genetic Organization of Nylon-Oligomer-Degrading Enzymes from Alkalophilic Bacterium, Agromyces sp. KY5R

A 15-kb gene locus including nylon-oligomer-degrading genes from the chromosome of an alkalophilic bacterium, Agromyces sp. KY5R, was cloned and sequenced. The genetic organization was similar to the DNA region flanked by directly repeated IS 6100 sequences on the nylon-oligomer-degradative plasmid...

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Veröffentlicht in:	Journal of bioscience and bioengineering 2007-12, Vol.104 (6), p.521-524
Hauptverfasser:	Yasuhira, Kengo, Uedo, Yuki, Takeo, Masahiro, Kato, Dai-Ichiro, Negoro, Seiji
Format:	Artikel
Sprache:	eng
Schlagworte:	6-aminohexanoate-oligomer hydrolase Actinomycetales - enzymology Actinomycetales - genetics Agromyces alkalophilic bacterium Amidohydrolases - genetics BACTERIA Base Sequence BIODEGRADACION BIODEGRADATION Biological and medical sciences Biotechnology Chromosome Mapping ENZIMAS ENZYME ENZYMES FIBRAS SINTETICAS FIBRE SYNTHETIQUE Fundamental and applied biological sciences. Psychology Gene Rearrangement - genetics IS 6100 Molecular Sequence Data nylon oligomer SYNTHETIC FIBRES
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Zusammenfassung:	A 15-kb gene locus including nylon-oligomer-degrading genes from the chromosome of an alkalophilic bacterium, Agromyces sp. KY5R, was cloned and sequenced. The genetic organization was similar to the DNA region flanked by directly repeated IS 6100 sequences on the nylon-oligomer-degradative plasmid pOAD2. However, we found several genetic rearrangements between the two DNA regions. Here, we discuss the possible mechanisms underlying the genetic rearrangements.
ISSN:	1389-1723 1347-4421
DOI:	10.1263/jbb.104.521