Fetal heart rate patterns in postasphyxiated fetal lambs with brain damage

Objective: We previously showed that in asphyxiated fetal lambs the duration of hypotension correlated well with the severity of histologic damage to the brain, whereas the duration of bradycardia did not. This study compares fetal heart rate patterns with the degree of histologic damage to the brai...

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Veröffentlicht in:	American journal of obstetrics and gynecology 1998-11, Vol.179 (5), p.1329-1337
Hauptverfasser:	Ikeda, Tomoaki, Murata, Yuji, Quilligan, Edward J., Parer, Julian T., Theunissen, Ingrid M., Cifuentes, Paula, Doi, Shigeharu, Park, Soung-Day
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals asphyxia Asphyxia - complications Asphyxia - physiopathology Biological and medical sciences Blood Pressure - physiology Brain Damage, Chronic - etiology Constriction, Pathologic Diseases of mother, fetus and pregnancy Female Fetal Diseases - physiopathology fetal heart rate pattern fetal lambs Gynecology. Andrology. Obstetrics Heart Rate, Fetal - physiology Humans Infant, Newborn Medical sciences Pregnancy Pregnancy. Fetus. Placenta Sheep - embryology Time Factors Umbilical Cord Umbilical cord occlusion
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Zusammenfassung:	Objective: We previously showed that in asphyxiated fetal lambs the duration of hypotension correlated well with the severity of histologic damage to the brain, whereas the duration of bradycardia did not. This study compares fetal heart rate patterns with the degree of histologic damage to the brain. Study Design: Twelve chronically instrumented near-term fetal lambs were subjected to asphyxia by umbilical cord occlusion until fetal arterial pH was
ISSN:	0002-9378 1097-6868
DOI:	10.1016/S0002-9378(98)70156-5