Diabetic ketoacidosis in adults--update of an old complication

Diabetic ketoacidosis is an acute complication of Diabetes Mellitus characterized by hyperglycemia, metabolic acidosis, dehydration, and ketosis, in patients with profound insulin deficiency. It occurs predominantly in patients with type 1 diabetes and is frequently precipitated by infections, insul...

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Veröffentlicht in:	Arquivos brasileiros de endocrinologia e metabologia 2007-12, Vol.51 (9), p.1434-1447
Hauptverfasser:	Barone, Bianca, Rodacki, Melanie, Cenci, Maria Claudia Peixoto, Zajdenverg, Lenita, Milech, Adolpho, Oliveira, José Egidio P de
Format:	Artikel
Sprache:	por
Schlagworte:	Adult Diabetes Mellitus, Type 1 - complications Diabetes Mellitus, Type 1 - diagnosis Diabetes Mellitus, Type 1 - physiopathology Diabetes Mellitus, Type 2 - complications Diabetes Mellitus, Type 2 - diagnosis Diabetes Mellitus, Type 2 - physiopathology Diabetic Ketoacidosis - diagnosis Diabetic Ketoacidosis - physiopathology Diabetic Ketoacidosis - therapy Humans
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Beschreibung
Zusammenfassung:	Diabetic ketoacidosis is an acute complication of Diabetes Mellitus characterized by hyperglycemia, metabolic acidosis, dehydration, and ketosis, in patients with profound insulin deficiency. It occurs predominantly in patients with type 1 diabetes and is frequently precipitated by infections, insulin withdrawal or undiagnosed type 1 diabetes. The authors review its pathophysiology, diagnostic criteria and treatment options in adults, as well as its complications.
ISSN:	0004-2730
DOI:	10.1590/S0004-27302007000900005