Relation between interstitial myocardial collagen and the degree of clinical impairment in Chagas’ disease

Relation between interstitial myocardial collagen and the degree of clinical impairment in Chagas’ disease

Cardiac performance is negatively associated with interstitial collagen in Chagas' cardiomyopathy. The magnitude of dysfunction is related to the degree of collagen, and this association seems to exhibit a threshold above it if definite cardiac deterioration occurs.

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Bibliographische Detailangaben
Veröffentlicht in:The American journal of cardiology 1999-08, Vol.84 (3), p.354-356
Hauptverfasser: Mady, Charles, Ianni, Barbara Maria, Arteaga, Edmundo, Montes, Gregorio Santiago, Caldini, Elia G, Andrade, Gisele, Giorgi, Maria Clementina P, Saldiva, Paulo Hilario N
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Biological and medical sciences
Cardiology
Cardiology. Vascular system
Cardiovascular disease
Chagas Disease - pathology
Chagas Disease - physiopathology
Collagen
Female
Fibrosis - diagnosis
Heart
Heart - diagnostic imaging
Humans
Male
Medical sciences
Middle Aged
Myocarditis. Cardiomyopathies
Myocardium - pathology
Radionuclide Ventriculography
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Beschreibung
Zusammenfassung:Cardiac performance is negatively associated with interstitial collagen in Chagas' cardiomyopathy. The magnitude of dysfunction is related to the degree of collagen, and this association seems to exhibit a threshold above it if definite cardiac deterioration occurs.
ISSN:0002-9149
1879-1913
DOI:10.1016/S0002-9149(99)00295-7