Low-dose oral iron absorption test in anaemic patients with and without iron deficiency determined by bone marrow iron content

: The low‐dose oral iron absorption test (OIAT) was performed in 85 consecutive anaemic patients referred for bone marrow examination in order to investigate the ability of the test to predict bone marrow iron stores and to differentiate between different categories of anaemia. Eight patients were e...

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Veröffentlicht in:European journal of haematology 1999-08, Vol.63 (2), p.103-111
Hauptverfasser: Jensen, Nanna M., Brandsborg, Margrethe, Boesen, Anne M., Yde, Hans, Dahlerup, Jens F.
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Sprache:eng
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Zusammenfassung:: The low‐dose oral iron absorption test (OIAT) was performed in 85 consecutive anaemic patients referred for bone marrow examination in order to investigate the ability of the test to predict bone marrow iron stores and to differentiate between different categories of anaemia. Eight patients were excluded for technical reasons. Test results from 77 patients are presented as Cmax (μmol/l): the maximum increase in S‐iron measured during a 3 h period after administration of 10 mg oral iron sulfate. Iron deficiency was defined as the absence of stainable iron in bone marrow aspirates. Cmax was higher in 46 iron deficient patients [3 (median); 0 and 13 (1st and 3rd quartiles); 0–40 (range)] than in 31 non‐iron‐deficient patients (0; 0 and 2; 0–4) (p
ISSN:0902-4441
1600-0609
DOI:10.1111/j.1600-0609.1999.tb01123.x