Epitope analysis of staphylococcal enterotoxin A using different synthetic peptides
The antigenic determinants (or epitopes) of staphylococcal enterotoxin A (SEA) were analyzed using synthetic peptides and rabbit antibodies to their corresponding peptides. Of 12 different synthetic peptides tested, peptides A-1 (corresponding to the amino acid sequence 1-20), A-5 (81-100), and A-8...
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Veröffentlicht in: | Journal of Veterinary Medical Science 1998, Vol.60(9), pp.993-996 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | The antigenic determinants (or epitopes) of staphylococcal enterotoxin A (SEA) were analyzed using synthetic peptides and rabbit antibodies to their corresponding peptides. Of 12 different synthetic peptides tested, peptides A-1 (corresponding to the amino acid sequence 1-20), A-5 (81-100), and A-8 (141-160) were reactive with anti-SEA antibodies. However, all synthetic peptides were found to elicit antibodies reactive with native SEA molecule. These findings suggest that native SEA molecule contains at least 3 different antigenic determinants. |
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ISSN: | 0916-7250 1347-7439 |
DOI: | 10.1292/jvms.60.993 |