Relationships between dehydroepiandrosterone-sulphate and anthropometric, metabolic and hormonal variables in a large cohort of obese women

OBJECTIVE The aim of the present study was to measure dehydroepiandrosterone‐sulphate (DHEA‐S) levels in obesity and assess the relationships between DHEA‐S and anthropometric, metabolic and hormonal variables. SUBJECTS AND METHODS We evaluated the serum DHEA‐S levels in 217 obese but otherwise norm...

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Veröffentlicht in:	Clinical endocrinology (Oxford) 1999-05, Vol.50 (5), p.595-600
Hauptverfasser:	Maccario, Mauro, Mazza, Enrico, Ramunni, Josefina, Oleandri, Salvatore E., Savio, Paola, Grottoli, Silvia, Rossetto, Ruth, Procopio, Massimo, Gauna, Carlotta, Ghigo, Ezio
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Androstenedione - blood Biological and medical sciences Case-Control Studies Dehydroepiandrosterone Sulfate - blood Female Glucose Tolerance Test Humans Hydrocortisone - urine Insulin - blood Insulin-Like Growth Factor I - analysis Medical sciences Metabolic diseases Middle Aged Obesity Obesity - blood Regression Analysis Testosterone - blood Triiodothyronine - blood
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Zusammenfassung:	OBJECTIVE The aim of the present study was to measure dehydroepiandrosterone‐sulphate (DHEA‐S) levels in obesity and assess the relationships between DHEA‐S and anthropometric, metabolic and hormonal variables. SUBJECTS AND METHODS We evaluated the serum DHEA‐S levels in 217 obese but otherwise normal female subjects (age (mean ± SEM): 39.4 ± 0.9, range 18–67 years, body mass index (BMI) = 36.1 ± 0.4, range 27.1–57.1 kg/m2). RESULTS DHEA‐S levels showed an age‐dependent fall similar to that observed in normal women (n = 156, age 46.2 ± 1.2, range 22–69 years, BMI
ISSN:	0300-0664 1365-2265
DOI:	10.1046/j.1365-2265.1999.00692.x