Why is coeliac disease endemic in the people of the Sahara?

The prevalence of antiendomysial antibody (AEA) in 989 Saharawi children was 5.6%. Intestinal biopsies in a subsample confirmed that AEA is a marker of coeliac disease in people living in a developing country.

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Bibliographische Detailangaben
Veröffentlicht in:	The Lancet (British edition) 1999-08, Vol.354 (9179), p.647-648
Hauptverfasser:	Catassi, Carlo, Ratsch, IIse-Maria, Gandolfi, Lenora, Pratesi, Riccardo, Fabiani, Elisabetta, Asmar, Ramzi El, Frijia, Maria, Bearzi, Italo, Vizzoni, Luciano
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Africa, Northern - epidemiology Autoantibodies - analysis Biopsy Celiac Disease - diagnosis Celiac Disease - epidemiology Celiac Disease - pathology Child Child, Preschool Developing countries Endemic Diseases Female Humans Immunoglobulin A - analysis Infant Intestines - pathology LDCs Male Medical disorders Medical research Muscle, Smooth - immunology Native peoples
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Beschreibung
Zusammenfassung:	The prevalence of antiendomysial antibody (AEA) in 989 Saharawi children was 5.6%. Intestinal biopsies in a subsample confirmed that AEA is a marker of coeliac disease in people living in a developing country.
ISSN:	0140-6736 1474-547X
DOI:	10.1016/S0140-6736(99)02609-4