Levels of soluble interleukin-2 receptor in the sera and skin tissue fluids of patients with vitiligo

Levels of soluble interleukin-2 receptor in the sera and skin tissue fluids of patients with vitiligo

In order to study the possible role of soluble interleukin-2 receptor (sIL-2R) in the pathogenesis of vitiligo, we measured the levels of sIL-2R in the sera and the tissue fluids from skin lesions and uninvolved skin from 41 patients with vitiligo, using the method of sandwich ELISA with monoclonal...

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Veröffentlicht in:Journal of dermatological science 1999-09, Vol.21 (1), p.59-62
Hauptverfasser: Caixia, Tu, Hongwen, Fu, Xiran, Lin
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Adult
Body Fluids - metabolism
Disease Progression
Enzyme-Linked Immunosorbent Assay
Female
Humans
Interleukin-2
Male
Middle Aged
Receptor
Receptors, Interleukin-2 - blood
Receptors, Interleukin-2 - metabolism
Serum
Skin - immunology
Skin - metabolism
Skin tissue fluid
Solubility
Vitiligo
Vitiligo - blood
Vitiligo - metabolism
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Zusammenfassung:In order to study the possible role of soluble interleukin-2 receptor (sIL-2R) in the pathogenesis of vitiligo, we measured the levels of sIL-2R in the sera and the tissue fluids from skin lesions and uninvolved skin from 41 patients with vitiligo, using the method of sandwich ELISA with monoclonal and polyclonal antibodies. The results showed that the overall level of serum sIL-2R from patients with vitiligo was significantly higher than that from normal control group ( P
ISSN:0923-1811
1873-569X
DOI:10.1016/S0923-1811(99)00029-8