Infection of a Left Ventricular Aneurysm and Massive Splenomegaly Demonstrated by In-111-Labeled Leukocyte Scintigraphy

When septicemia has failed to resolve after appropriate antibiotic therapy, labeled leukocyte scintigraphy is often valuable to locate focal sites of infection. In this case, probable infection of a left ventricular aneurysm, the sequela of an old myocardial infarction, was demonstrated. Massive splenomegaly due to portal vein stenosis after prior orthotopic liver transplantation also was depicted. In previously reported cases of infected left ventricular aneurysms, there usually has been prior myocardial infarction. As in this case, associated mural thrombus and false aneurysms have been reported. Demonstration by labeled leukocyte scintigraphy has not been previously reported.