Herpes simplex virus type 2 DNA detected in cerebrospinal fluid of 9 patients with Mollaret's meningitis

We present clinical and virological data on 9 patients, 7 women and 2 men aged 31–56 years, with recurrent aseptic meningitis (Mollaret's meningitis). Polymerase chain reaction detected Herpes simplex virus type 2 DNA in cerebrospinal fluid samples from all patients collected during their lates...

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Veröffentlicht in:	Acta neurologica Scandinavica 1998-09, Vol.98 (3), p.209-212
Hauptverfasser:	Jensenius, M., Myrvang, B., Størvold, G., Bucher, A., Hellum, K. B., Bruu, A.‐L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult aseptic meningitis Biological and medical sciences DNA, Viral - cerebrospinal fluid Female Herpes Genitalis - cerebrospinal fluid Herpes Genitalis - diagnosis Herpes Genitalis - virology Herpes simplex virus type 2 Herpesvirus 2, Human - genetics Human viral diseases Humans Infectious diseases Male Medical sciences Meningitis, Aseptic - cerebrospinal fluid Meningitis, Aseptic - diagnosis Meningitis, Aseptic - virology Meningitis, Viral - cerebrospinal fluid Meningitis, Viral - diagnosis Meningitis, Viral - virology Middle Aged polymerase chain reaction Recurrence Viral diseases Viral diseases of the nervous system
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Beschreibung
Zusammenfassung:	We present clinical and virological data on 9 patients, 7 women and 2 men aged 31–56 years, with recurrent aseptic meningitis (Mollaret's meningitis). Polymerase chain reaction detected Herpes simplex virus type 2 DNA in cerebrospinal fluid samples from all patients collected during their latest attacks of meningitis. Six patients had no history of genital herpes. Only 1 patient was offered prophylactic antiviral treatment during the study period (45 months).
ISSN:	0001-6314 1600-0404
DOI:	10.1111/j.1600-0404.1998.tb07296.x