Corneal endothelial changes in patients with chronic renal failure

PURPOSE: To evaluate the morphologic changes of the corneal endothelium in patients with chronic renal failure. METHODS: Twenty corneas of 20 patients with chronic renal failure undergoing hemodialysis were examined by wide-field specular microscopy. Twenty normal corneas from 20 healthy age-matched...

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Veröffentlicht in:	American journal of ophthalmology 1999-08, Vol.128 (2), p.234-236
Hauptverfasser:	Ohguro, Nobuyuki, Matsuda, Mamoru, Fukuda, Masakatsu
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Biological and medical sciences Cell Count Cell Size Corneal Diseases - etiology Corneal Diseases - pathology Endothelium, Corneal - pathology Humans Investigative techniques, diagnostic techniques (general aspects) Kidney Failure, Chronic - complications Kidney Failure, Chronic - therapy Medical sciences Ophthalmology Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Renal Dialysis
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Zusammenfassung:	PURPOSE: To evaluate the morphologic changes of the corneal endothelium in patients with chronic renal failure. METHODS: Twenty corneas of 20 patients with chronic renal failure undergoing hemodialysis were examined by wide-field specular microscopy. Twenty normal corneas from 20 healthy age-matched subjects were enrolled as control corneas. RESULTS: Despite normal endothelial cell density, the corneal endothelium of patients with chronic renal failure showed marked polymegethism and pleomorphism. CONCLUSION: Polymegethism and pleomorphism of the corneal endothelium are found in patients with chronic renal failure.
ISSN:	0002-9394 1879-1891
DOI:	10.1016/S0002-9394(99)00086-0