Novel A,B,E-Ring-Modified Camptothecins Displaying High Lipophilicity and Markedly Improved Human Blood Stabilities

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Bibliographische Detailangaben
Veröffentlicht in:	Journal of medicinal chemistry 1999-08, Vol.42 (16), p.3018-3022
Hauptverfasser:	Bom, David, Curran, Dennis P, Chavan, Ashok J, Kruszewski, Stefan, Zimmer, Stephen G, Fraley, Kimberly A, Burke, Thomas G
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic agents Biological and medical sciences Camptothecin - analogs & derivatives Camptothecin - blood Camptothecin - chemical synthesis Camptothecin - chemistry Chromatography, High Pressure Liquid Dimyristoylphosphatidylcholine - chemistry Drug Stability Enzyme Inhibitors - chemical synthesis Enzyme Inhibitors - chemistry Enzyme Inhibitors - pharmacology Fluorescence Polarization General aspects Humans Hydrolysis Medical sciences Pharmacology. Drug treatments Phosphatidylglycerols - chemistry Spectrometry, Fluorescence Structure-Activity Relationship Topoisomerase I Inhibitors
Online-Zugang:	Volltext
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