Effects of β-adrenergic blocking therapy on left ventricular diastolic relaxation properties in patients with dilated cardiomyopathy

The hemodynamic mechanism for the improvement in left ventricle (LV) end-diastolic pressure in cardiomyopathy patients treated with beta-adrenergic blocking agents is controversial. We hypothesized that the salutary effect of this kind of therapy on LV end-diastolic pressure would be indicative of a...

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Veröffentlicht in:	Circulation (New York, N.Y.) N.Y.), 1999-08, Vol.100 (7), p.729-735
Hauptverfasser:	KIM, M. H, DEVLIN, W. H, DAS, S. K, PETRUSHA, J, MONTGOMERY, D, STARLING, M. R
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic beta-Antagonists - pharmacology Adrenergic beta-Antagonists - therapeutic use Biological and medical sciences Cardiomyopathy, Dilated - drug therapy Cardiomyopathy, Dilated - physiopathology Cardiovascular system Diastole - drug effects Female Heart Rate - drug effects Humans Male Medical sciences Metoprolol - pharmacology Metoprolol - therapeutic use Middle Aged Miscellaneous Muscle Relaxation - drug effects Myocardial Contraction - drug effects Pharmacology. Drug treatments Stroke Volume - drug effects Ventricular Function, Left - drug effects
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