Evaluation of natural Psoroptes ovis (Acarina: Psoroptidae) soluble proteins as candidate vaccine immunogens

In this study potential vaccine candidate immunogens were identified and evaluated in a vaccine challenge trial. Calves vaccinated with a partially purified fraction of Psoroptes ovis-soluble proteins had 8 of 14 calves free of palpable lesions 8 wk after a challenge infestation. A self-grooming beh...

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Veröffentlicht in:	Journal of medical entomology 1998-09, Vol.35 (5), p.861-871
Hauptverfasser:	Pruett, J.H. (Knipling-Bushland U.S. Livestock Insects Research Laboratory, USDA, ARS, Kerriville, TX.), Temeyer, K.B, Fisher, W.F, Beetham, P.K, Kunz, S.E
Format:	Artikel
Sprache:	eng
Schlagworte:	ANIMAL PROTEINS Animals Antibody Formation ANTIGENE ANTIGENOS ANTIGENS Applied microbiology BEHAVIOUR Biological and medical sciences CALVES Cattle Cattle Diseases - immunology Cattle Diseases - parasitology Cattle Diseases - prevention & control CATTLE SCABIES COMPORTAMIENTO COMPORTEMENT DENSIDAD DE LA POBLACION DENSITE DE POPULATION DISEASE RESISTANCE ECTOPARASITOSES ENFERMEDADES PARASITARIAS Enzyme-Linked Immunosorbent Assay Female Fundamental and applied biological sciences. Psychology GROOMING IMMUNE RESPONSE LESION LESIONES LESIONS Male Microbiology Mite Infestations - immunology Mite Infestations - prevention & control Mite Infestations - veterinary Mites - immunology PARASITOSE PARASITOSES POPULATION DENSITY PROTEINAS PROTEINE PROTEINS PRUEBAS CUTANEAS PSOROPTES OVIS Psoroptidae REPONSE IMMUNITAIRE RESISTANCE AUX MALADIES RESISTENCIA A LA ENFERMEDAD RESPUESTA INMUNOLOGICA SKIN TESTS TERNERO TEST CUTANE VACCIN VACCINATION VACCINE DEVELOPMENT VACCINES Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects) VACUNA VACUNACION VEAU
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Zusammenfassung:	In this study potential vaccine candidate immunogens were identified and evaluated in a vaccine challenge trial. Calves vaccinated with a partially purified fraction of Psoroptes ovis-soluble proteins had 8 of 14 calves free of palpable lesions 8 wk after a challenge infestation. A self-grooming behavioral response elicited by a pruritic immediate-type allergic reaction was believed to be an effector in protecting the vaccinated calves from a clinical P. ovis infestation
ISSN:	0022-2585 1938-2928
DOI:	10.1093/jmedent/35.5.861