Evidence for an Ontogenetic Basis for Circadian Coordination of Cancer Cell Proliferation

If cell proliferation in spontaneous human cancer is coordinated within the day, then a finding of circadian rhythm in any aspect of cancer cell proliferation would provide a mechanism supporting the likelihood that cancer cell susceptibility itself waxes and wanes predictably throughout each day.

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Bibliographische Detailangaben
Veröffentlicht in:	JNCI : Journal of the National Cancer Institute 1998-10, Vol.90 (19), p.1480-1484
Hauptverfasser:	Hrushesky, William J. M., Lannin, Donald, Haus, Erhard
Format:	Artikel
Sprache:	eng
Schlagworte:	Body Temperature Cancer Carcinoma, Squamous Cell - physiopathology Carcinoma, Squamous Cell - secondary Carcinoma, Squamous Cell - urine Circadian Rhythm Female Genetics Humans Hydrocortisone - urine Lymphatic Metastasis - physiopathology Middle Aged Mitosis Mitotic Index Skin Neoplasms - physiopathology Skin Neoplasms - secondary Skin Neoplasms - urine
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Beschreibung
Zusammenfassung:	If cell proliferation in spontaneous human cancer is coordinated within the day, then a finding of circadian rhythm in any aspect of cancer cell proliferation would provide a mechanism supporting the likelihood that cancer cell susceptibility itself waxes and wanes predictably throughout each day.
ISSN:	0027-8874 1460-2105
DOI:	10.1093/jnci/90.19.1480