The Discrepancy in Hardness between Clinical and Histopathological Findings in Localized Scleroderma Treated with PUVA

Topical PUVA therapy was applied to a patient with localized scleroderma. Her localized scleroderma responded very well to the topical PUVA therapy, i.e., her sclerotic skin softened to normal skin texture. However, despite this dramatic clinical change the histopathological findings did not change...

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Veröffentlicht in:	Journal of dermatology 1998-08, Vol.25 (8), p.544-546
Hauptverfasser:	Yamaguchi, Keiko, Takeuchi, Izuho, Yoshii, Noriko, Gushi, Akira, Kanekura, Takuro, Kanzaki, Tamotsu
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Arm Female histopathology Humans photochemotherapy PUVA Therapy scleroderma Scleroderma, Localized - drug therapy Scleroderma, Localized - pathology softening
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Beschreibung
Zusammenfassung:	Topical PUVA therapy was applied to a patient with localized scleroderma. Her localized scleroderma responded very well to the topical PUVA therapy, i.e., her sclerotic skin softened to normal skin texture. However, despite this dramatic clinical change the histopathological findings did not change at all and were still “hard”.
ISSN:	0385-2407 1346-8138
DOI:	10.1111/j.1346-8138.1998.tb02452.x