Effect of aldosterone on kinetics of intracellular sodium in cortical portion of collecting ducts in rat kidney

We studied the effect of protein kinase C inhibitor RO-31-8220 (10⁻⁷ M) on rapid nongenomic effect of aldosterone in cells of isolated segment of distal region of collecting duct in rat kidney. Experiments with fluorescent dye Na-Green showed that the inhibitor abolished the modulating effect of ald...

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Veröffentlicht in:	Bulletin of experimental biology and medicine 2008-08, Vol.146 (2), p.192-195
Hauptverfasser:	Logvinenko, N. S, Solenov, E. I, Ivanova, L. N
Format:	Artikel
Sprache:	eng
Schlagworte:	aldosterone Aldosterone - administration & dosage Aldosterone - metabolism Animals Biomedical and Life Sciences Biomedicine Cell Biology Enzyme Inhibitors - pharmacology Fluorescence General Pathology and Pathophysiology In Vitro Techniques Indoles - pharmacology Internal Medicine intracellular sodium Intracellular Space - metabolism Kidney Tubules, Collecting - drug effects Kidney Tubules, Collecting - metabolism kidneys Laboratory Medicine Microdissection Pathology protein kinase C Protein Kinase C - antagonists & inhibitors Rats Sodium - metabolism
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