Restructuring of the thyroid gland in primary hypothyroidism under the influence of intermittent hypobaric hypoxia

We studied the effect of intermittent hypobaric hypoxia on morphofunctional characteristics of the thyroid gland during experimental hypothyroidism. Functional activity of the thyroid gland increased in the early period of hypoxia. Morphofunctional parameters reached a constant level with increasing...

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Veröffentlicht in:	Bulletin of experimental biology and medicine 2008-05, Vol.145 (5), p.647-649
Hauptverfasser:	Tararak, T. J., Vasil’eva, V. V., Balykin, M. V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptation, Physiological Animals Atmospheric Pressure Biomedical and Life Sciences Biomedicine Cell Biology Hypothyroidism - pathology Hypothyroidism - physiopathology Hypothyroidism - therapy Hypoxia Internal Medicine Laboratory Medicine Male Organ Size Pathology Rats Thyroid Gland - pathology Thyroid Gland - physiopathology Time Factors
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Zusammenfassung:	We studied the effect of intermittent hypobaric hypoxia on morphofunctional characteristics of the thyroid gland during experimental hypothyroidism. Functional activity of the thyroid gland increased in the early period of hypoxia. Morphofunctional parameters reached a constant level with increasing the duration of hypoxia to 7–15 days. A new functional level was characterized by increased activity and normal function of glandular cells.
ISSN:	0007-4888 1573-8221
DOI:	10.1007/s10517-008-0163-x