Sensitization of the thymus to hypoplastic effect of glucocorticoids after long-term hypokinetic stress

Long-term hypokinesia increases sensitivity of the thymus to the hypoplastic effect of glucocorticoid preparation triamcinolone acetonide by potentiating the proapoptotic effect of the glucocorticoid.

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Bibliographische Detailangaben
Veröffentlicht in:	Bulletin of experimental biology and medicine 2008-07, Vol.146 (1), p.36-37
Hauptverfasser:	Tseilikman, V. E, Filimonova, T. A, Boyarinova, N. V, Sibiryak, S. V, Kozochkin, D. A, Sinitsky, A. I
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals apoptosis Biomedical and Life Sciences Biomedicine Cell Biology Cell Cycle - drug effects Female General Pathology and Pathophysiology Glucocorticoids - pharmacology hypokinesia Immobilization - physiology Immobilization - psychology Internal Medicine Laboratory Medicine Male Motor Activity - physiology Pathology Rats Rats, Wistar Restraint, Physical - physiology Restraint, Physical - psychology Stress, Psychological Thymus (Lamiaceae) Thymus Gland - cytology Thymus Gland - drug effects Thymus Gland - metabolism Triamcinolone - chemistry Triamcinolone - pharmacology triamcinolone acetonide
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Beschreibung
Zusammenfassung:	Long-term hypokinesia increases sensitivity of the thymus to the hypoplastic effect of glucocorticoid preparation triamcinolone acetonide by potentiating the proapoptotic effect of the glucocorticoid.
ISSN:	0007-4888 1573-8221
DOI:	10.1007/s10517-008-0201-8