Tissue remodeling and angiogenesis in asthma: the role of the eosinophil

Tissue remodeling and angiogenesis in asthma: the role of the eosinophil

This review covers the role of eosinophils in asthma-associated tissue remodeling and angiogenesis focusing on angiogenesis which is a recently discovered feature of asthma. In addition, novel directions for eosinophil-targeted/angiogenesis-targeted pharmacological intervention are discussed as new...

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Veröffentlicht in:Therapeutic advances in respiratory disease 2008-06, Vol.2 (3), p.163-171
Hauptverfasser: Nissim Ben Efraim, A H, Levi-Schaffer, F
Format: Artikel
Sprache:eng
Schlagworte:
Angiogenesis Inhibitors - pharmacology
Animals
Asthma - immunology
Asthma - physiopathology
Eosinophils - physiology
Humans
Lung - physiopathology
Neovascularization, Pathologic - physiopathology
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Zusammenfassung:This review covers the role of eosinophils in asthma-associated tissue remodeling and angiogenesis focusing on angiogenesis which is a recently discovered feature of asthma. In addition, novel directions for eosinophil-targeted/angiogenesis-targeted pharmacological intervention are discussed as new approaches in the treatment of asthma.
ISSN:1753-4658
DOI:10.1177/1753465808092281