Steroids from the roots of Nerium oleander
Two new cardenolides, 3beta-hydroxy-5alpha-carda-14(15), 20(22)-dienolide (beta-anhydroepidigitoxigenin) (1) and 3beta-O-(D-digitalosyl)-21-hydroxy-5beta-carda-8,14,16 , 20(22)-tetraenolide (neriumogenin-A-3beta-D-digitaloside) (2), and two known compounds, proceragenin and neridienone A (3), have b...
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| Veröffentlicht in: | Journal of natural products (Washington, D.C.) D.C.), 1999-07, Vol.62 (7), p.1065-1067 |
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| container_end_page | 1067 |
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| container_issue | 7 |
| container_start_page | 1065 |
| container_title | Journal of natural products (Washington, D.C.) |
| container_volume | 62 |
| creator | Huq, M.M Jabbar, A Rashid, M.A Hasan, C.M Ito, C Furukawa, H |
| description | Two new cardenolides, 3beta-hydroxy-5alpha-carda-14(15), 20(22)-dienolide (beta-anhydroepidigitoxigenin) (1) and 3beta-O-(D-digitalosyl)-21-hydroxy-5beta-carda-8,14,16 , 20(22)-tetraenolide (neriumogenin-A-3beta-D-digitaloside) (2), and two known compounds, proceragenin and neridienone A (3), have been isolated from the roots of Nerium oleander. The structures of 1 and 2 were elucidated on the basis of spectral data interpretation. |
| doi_str_mv | 10.1021/np990031b |
| format | Article |
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The structures of 1 and 2 were elucidated on the basis of spectral data interpretation.</description><identifier>ISSN: 0163-3864</identifier><identifier>EISSN: 1520-6025</identifier><identifier>DOI: 10.1021/np990031b</identifier><identifier>PMID: 10425146</identifier><identifier>CODEN: JNPRDF</identifier><language>eng</language><publisher>Washington, DC: American Chemical Society</publisher><subject>Biological and medical sciences ; Carbohydrate Sequence ; cardenolides ; chemical constituents of plants ; chemical structure ; General pharmacology ; Magnetic Resonance Spectroscopy ; Medical sciences ; Molecular Sequence Data ; Nerium oleander ; Pharmacognosy. Homeopathy. Health food ; Pharmacology. 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Nat. Prod</addtitle><description>Two new cardenolides, 3beta-hydroxy-5alpha-carda-14(15), 20(22)-dienolide (beta-anhydroepidigitoxigenin) (1) and 3beta-O-(D-digitalosyl)-21-hydroxy-5beta-carda-8,14,16 , 20(22)-tetraenolide (neriumogenin-A-3beta-D-digitaloside) (2), and two known compounds, proceragenin and neridienone A (3), have been isolated from the roots of Nerium oleander. The structures of 1 and 2 were elucidated on the basis of spectral data interpretation.</description><subject>Biological and medical sciences</subject><subject>Carbohydrate Sequence</subject><subject>cardenolides</subject><subject>chemical constituents of plants</subject><subject>chemical structure</subject><subject>General pharmacology</subject><subject>Magnetic Resonance Spectroscopy</subject><subject>Medical sciences</subject><subject>Molecular Sequence Data</subject><subject>Nerium oleander</subject><subject>Pharmacognosy. Homeopathy. Health food</subject><subject>Pharmacology. Drug treatments</subject><subject>Plant Roots - chemistry</subject><subject>Plants, Medicinal - chemistry</subject><subject>roots</subject><subject>spectral analysis</subject><subject>Spectrophotometry, Infrared</subject><subject>Spectrophotometry, Ultraviolet</subject><subject>Steroids - chemistry</subject><subject>Steroids - isolation & purification</subject><issn>0163-3864</issn><issn>1520-6025</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1999</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpF0EtLxDAUBeAgio6PhX9AuxAXQjW5eTRZim-QUenoNmSaW622kzHpgP57CzPq6i7Ox4FzCdln9JRRYGezuTGUcjZdIyMmgeaKglwnI8oUz7lWYotsp_ROB0ON3CRbjAqQTKgROSl7jKHxKatj6LL-DbMYQp-yUGdjjM2iy0KLbuYx7pKN2rUJ91Z3hzxfX00ubvP7h5u7i_P7vAaj-1zUFWqnvEDg3KGSvADQstYIlYZKoHHeg5SuEF7pqQahCo_MSKG4YX7Kd8jxsncew-cCU2-7JlXYtm6GYZGsMgZAaTHAgxVcTDv0dh6bzsVv-7tuAEcr4FLl2jq6WdWkf8c0MxoGli9Zk3r8-otd_LCq4IW0k8fSvvCnS1OOqS0Hf7j0tQvWvcah8rkEyjgFM3y7UPwHCcBznw</recordid><startdate>19990701</startdate><enddate>19990701</enddate><creator>Huq, M.M</creator><creator>Jabbar, A</creator><creator>Rashid, M.A</creator><creator>Hasan, C.M</creator><creator>Ito, C</creator><creator>Furukawa, H</creator><general>American Chemical Society</general><general>American Society of Pharmacognosy</general><scope>FBQ</scope><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>19990701</creationdate><title>Steroids from the roots of Nerium oleander</title><author>Huq, M.M ; Jabbar, A ; Rashid, M.A ; Hasan, C.M ; Ito, C ; Furukawa, H</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-f298t-4fce8a6d4e233ae65372285f8e2c82c4e9add255a74d68b82467de19546391db3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1999</creationdate><topic>Biological and medical sciences</topic><topic>Carbohydrate Sequence</topic><topic>cardenolides</topic><topic>chemical constituents of plants</topic><topic>chemical structure</topic><topic>General pharmacology</topic><topic>Magnetic Resonance Spectroscopy</topic><topic>Medical sciences</topic><topic>Molecular Sequence Data</topic><topic>Nerium oleander</topic><topic>Pharmacognosy. Homeopathy. Health food</topic><topic>Pharmacology. Drug treatments</topic><topic>Plant Roots - chemistry</topic><topic>Plants, Medicinal - chemistry</topic><topic>roots</topic><topic>spectral analysis</topic><topic>Spectrophotometry, Infrared</topic><topic>Spectrophotometry, Ultraviolet</topic><topic>Steroids - chemistry</topic><topic>Steroids - isolation & purification</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Huq, M.M</creatorcontrib><creatorcontrib>Jabbar, A</creatorcontrib><creatorcontrib>Rashid, M.A</creatorcontrib><creatorcontrib>Hasan, C.M</creatorcontrib><creatorcontrib>Ito, C</creatorcontrib><creatorcontrib>Furukawa, H</creatorcontrib><collection>AGRIS</collection><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of natural products (Washington, D.C.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Huq, M.M</au><au>Jabbar, A</au><au>Rashid, M.A</au><au>Hasan, C.M</au><au>Ito, C</au><au>Furukawa, H</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Steroids from the roots of Nerium oleander</atitle><jtitle>Journal of natural products (Washington, D.C.)</jtitle><addtitle>J. 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| source | MEDLINE; ACS Publications |
| subjects | Biological and medical sciences Carbohydrate Sequence cardenolides chemical constituents of plants chemical structure General pharmacology Magnetic Resonance Spectroscopy Medical sciences Molecular Sequence Data Nerium oleander Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Plant Roots - chemistry Plants, Medicinal - chemistry roots spectral analysis Spectrophotometry, Infrared Spectrophotometry, Ultraviolet Steroids - chemistry Steroids - isolation & purification |
| title | Steroids from the roots of Nerium oleander |
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