Steroids from the roots of Nerium oleander

Two new cardenolides, 3beta-hydroxy-5alpha-carda-14(15), 20(22)-dienolide (beta-anhydroepidigitoxigenin) (1) and 3beta-O-(D-digitalosyl)-21-hydroxy-5beta-carda-8,14,16 , 20(22)-tetraenolide (neriumogenin-A-3beta-D-digitaloside) (2), and two known compounds, proceragenin and neridienone A (3), have b...

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Veröffentlicht in:	Journal of natural products (Washington, D.C.) D.C.), 1999-07, Vol.62 (7), p.1065-1067
Hauptverfasser:	Huq, M.M, Jabbar, A, Rashid, M.A, Hasan, C.M, Ito, C, Furukawa, H
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Carbohydrate Sequence cardenolides chemical constituents of plants chemical structure General pharmacology Magnetic Resonance Spectroscopy Medical sciences Molecular Sequence Data Nerium oleander Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Plant Roots - chemistry Plants, Medicinal - chemistry roots spectral analysis Spectrophotometry, Infrared Spectrophotometry, Ultraviolet Steroids - chemistry Steroids - isolation & purification
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Zusammenfassung:	Two new cardenolides, 3beta-hydroxy-5alpha-carda-14(15), 20(22)-dienolide (beta-anhydroepidigitoxigenin) (1) and 3beta-O-(D-digitalosyl)-21-hydroxy-5beta-carda-8,14,16 , 20(22)-tetraenolide (neriumogenin-A-3beta-D-digitaloside) (2), and two known compounds, proceragenin and neridienone A (3), have been isolated from the roots of Nerium oleander. The structures of 1 and 2 were elucidated on the basis of spectral data interpretation.
ISSN:	0163-3864 1520-6025
DOI:	10.1021/np990031b