Palladium-Catalyzed γ-Selective and Stereospecific Allyl−Aryl Coupling between Allylic Acetates and Arylboronic Acids

Allyl−aryl coupling between allylic acetates and arylboronic acids took place in the presence of catalytic amounts of Pd(OAc)2, 1,10-phenanthroline, and AgSbF6 with high γ-selectivity and E/Z-selectivity. The reaction of an optically active allylic acetates with an α-stereogenic center proceeded with excellent α-to-γ chirality transfer with syn-selectivity and gave the corresponding optically active allyl−aryl coupling products with a stereogenic center at the benzylic position.