Cauda equina syndrome revealing neuroblastoma

Neuroblastoma is the most common solid tumor of childhood. Neurological involvement is rare resulting from cord or nerve compression. A 7-year-old child was hospitalized for cauda equina syndrome. MRI showed retroperitoneal lesion with dumbbell intradural spreading. Blood and urinary catecholamine l...

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Veröffentlicht in:Revue neurologique 2008-12, Vol.164 (12), p.1048-1051
Hauptverfasser: Bourezgui, M, Rafai, M A, El Moutawakkil, B, Boulaajaj, F Z, Sibai, M, Lezar, S, Adil, A, Benchkroun, S, Kadiri, R, Slassi, I
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Sprache:fre
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Zusammenfassung:Neuroblastoma is the most common solid tumor of childhood. Neurological involvement is rare resulting from cord or nerve compression. A 7-year-old child was hospitalized for cauda equina syndrome. MRI showed retroperitoneal lesion with dumbbell intradural spreading. Blood and urinary catecholamine level were elevated confirming the diagnosis of neuroblastoma. She was treated with chemotherapy alone with partial neurological recovery. Cauda equina compression revealing neuroblastoma is exceptional especially at an early phase in the youngest patients. Treatment is based on surgical resection and/or chemotherapy and/or radiation therapy. Long-term prognosis is sometimes poor with neurological sequels.
ISSN:0035-3787
DOI:10.1016/j.neurol.2008.03.023