Use of point-of-care test in identification of patients who can benefit from desmopressin during cardiac surgery: a randomised controlled trial

Platelet dysfunction is a major cause of excessive microvascular bleeding after cardiac surgery. A new point-of-care test (hemoSTATUS) can identify patients at risk of excessive bleeding. We aimed to find out whether patients who can benefit from desmopressin during cardiac surgery can be identified...

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Veröffentlicht in:The Lancet (British edition) 1999-07, Vol.354 (9173), p.106-110
Hauptverfasser: Despotis, George J, Levine, Vladimir, Saleem, Rao, Spitznagel, Edward, Joist, J Heinrich
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Sprache:eng
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Zusammenfassung:Platelet dysfunction is a major cause of excessive microvascular bleeding after cardiac surgery. A new point-of-care test (hemoSTATUS) can identify patients at risk of excessive bleeding. We aimed to find out whether patients who can benefit from desmopressin during cardiac surgery can be identified by this test. We enrolled 203 patients scheduled for elective cardiac surgery in a prospective, double-blind, placebo-controlled trial. Patients with abnormal hemoSTATUS clot-ratio results (
ISSN:0140-6736
1474-547X
DOI:10.1016/S0140-6736(98)12494-7