Effectiveness of Live, Attenuated Intranasal Influenza Virus Vaccine in Healthy, Working Adults: A Randomized Controlled Trial

CONTEXT Influenza virus is a major cause of illness, disruption to daily life, and increased use of health care in all age groups. OBJECTIVE To assess the safety and effectiveness of intranasally administered trivalent, live, attenuated influenza virus (LAIV) vaccine for reducing illness, absenteeis...

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Veröffentlicht in:	JAMA : the journal of the American Medical Association 1999-07, Vol.282 (2), p.137-144
Hauptverfasser:	Nichol, Kristin L, Mendelman, Paul M, Mallon, Kenneth P, Jackson, Lisa A, Gorse, Geoffrey J, Belshe, Robert B, Glezen, W. Paul, Wittes, Janet
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Intranasal Adult Biological and medical sciences Cost of Illness Disease Outbreaks Double-Blind Method Female Human viral diseases Humans Infectious diseases Influenza Influenza A virus Influenza A virus - immunology Influenza Vaccines - administration & dosage Influenza Vaccines - adverse effects Influenza Vaccines - immunology Influenza, Human - epidemiology Influenza, Human - prevention & control Linear Models Male Medical research Medical sciences Middle Aged Poisson Distribution Seasons Vaccines Vaccines, Attenuated - administration & dosage Vaccines, Attenuated - adverse effects Vaccines, Attenuated - immunology Viral diseases Viral diseases of the respiratory system and ent viral diseases Viruses
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