Of barn owls and bankers: a lush variety of α/β hydrolases

Of barn owls and bankers: a lush variety of α/β hydrolases

α/ β Hydrolase fold proteins are an important, diverse, widespread group of enzymes not yet fully exploited by structural biologists. We describe the current state of knowledge of this family, and suggest a smaller definition of the required core and some possible future avenues of exploration.

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Veröffentlicht in:Structure 1999-06, Vol.7 (6), p.R141-R146
Hauptverfasser: Heikinheimo, Pirkko, Goldman, Adrian, Jeffries, Cy, Ollis, David L
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Bacterial Proteins - chemistry
Evolution, Molecular
Humans
Hydrolases - chemistry
Models, Molecular
Plant Proteins - chemistry
Protein Folding
Protein Structure, Secondary
Space life sciences
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Zusammenfassung:α/ β Hydrolase fold proteins are an important, diverse, widespread group of enzymes not yet fully exploited by structural biologists. We describe the current state of knowledge of this family, and suggest a smaller definition of the required core and some possible future avenues of exploration.
ISSN:0969-2126
1878-4186
DOI:10.1016/S0969-2126(99)80079-3