Immunolocalization of tumor necrosis factor-alpha and its receptors in inflammatory myopathies

Adhesion molecule upregulation occurs in inflammatory myopathies, and is one of the myriad functions of tumor necrosis factor- α (TNF- α). TNF- α acts via two different receptors of 55 (TNF-R55) and 75 kD (TNF-R75). We immunolocalized TNF- α and its receptors in polymyositis, inclusion body myositis...

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Veröffentlicht in:	Neuromuscular disorders : NMD 1999-06, Vol.9 (4), p.239-246
Hauptverfasser:	De Bleecker, Jan L, Meire, Veronique I, Declercq, Wim, Van Aken, Elisabeth H
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, CD - biosynthesis Antigens, CD - genetics Dermatomyositis - metabolism Dermatomyositis - pathology Endothelium, Vascular - cytology Endothelium, Vascular - pathology Humans Immunohistochemistry Immunology Inflammatory myopathies Muscle, Skeletal - metabolism Muscle, Skeletal - pathology Myositis - metabolism Myositis - pathology Myositis, Inclusion Body - metabolism Myositis, Inclusion Body - pathology Pathology Polymyositis - metabolism Polymyositis - pathology Receptors, Tumor Necrosis Factor - biosynthesis Receptors, Tumor Necrosis Factor - genetics Receptors, Tumor Necrosis Factor - metabolism Receptors, Tumor Necrosis Factor, Type I Receptors, Tumor Necrosis Factor, Type II Tumor necrosis factor Tumor Necrosis Factor-alpha - metabolism Up-Regulation - physiology
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