Response to: Early regression of cervical lesions in HIV-seropositive women receiving highly active antiretroviral therapy, by Heard et al. AIDS 1998, 12:1459-1464

I am writing concerning what may be a statistical error and another possible statistical problem in the paper by Heard et al. Their conclusion of an `early regression of cervical lesions in HIV-seropositive women receiving HAART' is partly based on a finding that the reduction in the prevalence of squamous intra-epithelial lesions (SIL) from 69 to 53% among 49 HIV-infected women after highly active antiretroviral therapy (HAART) is significant at P < 0.0001.