Spinal tumors in infancy. A report of 48 cases

Spinal tumours in infancy are an infrequent oncological disorder. The clinical features, usually of insidious onset, are alterations in gait and a painful spine. To analyze the different histological types of spinal tumours seen in infancy and their form of presentation in our series. We reviewed th...

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Veröffentlicht in:Revista de neurologiá 1999-05, Vol.28 (9), p.863-867
Hauptverfasser: Pérez-Martínez, D A, Bueno, H J, Gutiérrez, F, López-Laso, E, Puente-Muñoz, A I, Esparza, J, Simón, R, Mateos, F
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Zusammenfassung:Spinal tumours in infancy are an infrequent oncological disorder. The clinical features, usually of insidious onset, are alterations in gait and a painful spine. To analyze the different histological types of spinal tumours seen in infancy and their form of presentation in our series. We reviewed the clinical histories of 48 patients with intraspinal tumours, aged under 15 years, whose reports of histological diagnosis had been sent to our centre. Of the patients studied, 17 were girls (35.4%) and 31 boys (64.6%) with an average age of 7.7 years. The histological diagnoses made most frequently were astrocytomas (22.9%) and lipomas (18.8%) followed by metastases (12.5%), ependymomas (8.3%) and Edwing's sarcoma (8.3%). The clinical features were present prior to diagnosis for between 1 and 6 months in 13 patients, and for less than one month in 9 patients. The presenting symptoms were alterations in gait and back pain in most patients. Exploratory tests were related to the involvement of long vias and second motor-neurone lesions. The main topographical findings were: in the axial plane the lesions were extradural (23 patients) and in the sagittal plane there was dorsal involvement (34 patients). Insidious, progressive alterations in gait together with continuous, nocturnal back pain are valuable data when a serious spinal disorder is to be suspected. Early diagnosis should be based on neuroimaging tests, essentially MR, in the patients in whom spinal cord involvement is considered.
ISSN:0210-0010