Methotrexate treatment for retained placental tissue

Three cases of placental polyps not responding to conventional medical and surgical treatment are presented. In all three cases, hCG in serum was negative but despite this a single injection of methotrexate successfully treated the condition. It is suggested that methotrexate acts not only on dividi...

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Veröffentlicht in:	European journal of obstetrics & gynecology and reproductive biology 1999-04, Vol.83 (2), p.127-129
Hauptverfasser:	Flam, F., Karlström, P.-O., Carlsson, Björn, Garoff, Lena
Format:	Artikel
Sprache:	eng
Schlagworte:	Abortifacient Agents, Nonsteroidal - therapeutic use Adult Biological and medical sciences Delivery. Postpartum. Lactation Disorders Female Folic Acid Antagonists - therapeutic use Gynecology. Andrology. Obstetrics Humans Medical sciences Methotrexate Methotrexate - therapeutic use Nucleic Acid Synthesis Inhibitors - therapeutic use Placenta, Retained - drug therapy Placental tissue Pregnancy
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Beschreibung
Zusammenfassung:	Three cases of placental polyps not responding to conventional medical and surgical treatment are presented. In all three cases, hCG in serum was negative but despite this a single injection of methotrexate successfully treated the condition. It is suggested that methotrexate acts not only on dividing trophoblastic cells but also has other effects.
ISSN:	0301-2115 1872-7654
DOI:	10.1016/S0301-2115(98)00270-X