Iridoid and seco-iridoid glucosides from Chioccoca alba (Rubiaceae)
Phytochemical investigation of Chioccoca alba afforded three new iridoids, alboside I, alboside II and alboside III, and a new seco-iridoid alboside V. Alboside IV showed moderate activity towards the DNA repair-deficient mutant RS321 of Saccharomyces cerevisiae. The structural elucidation of the ne...
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| Veröffentlicht in: | Phytochemistry (Oxford) 1999-07, Vol.51 (6), p.781-785 |
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| container_title | Phytochemistry (Oxford) |
| container_volume | 51 |
| creator | Carbonezi, Carlos Alberto Martins, Dirceu Young, Maria Claudia M Lopes, Marcia N Furlan, Maysa Rodrigues Filho, Edson Bolzani, Vanderlan da S |
| description | Phytochemical investigation of
Chioccoca alba afforded three new iridoids, alboside I, alboside II and alboside III, and a new
seco-iridoid alboside V. Alboside
IV showed moderate activity towards the DNA repair-deficient mutant RS321 of
Saccharomyces cerevisiae. The structural elucidation of the new compounds was performed by ES–MS and by 1D and 2D NMR spectroscopic methods. |
| doi_str_mv | 10.1016/S0031-9422(99)00105-3 |
| format | Article |
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Chioccoca alba afforded three new iridoids, alboside I, alboside II and alboside III, and a new
seco-iridoid alboside V. Alboside
IV showed moderate activity towards the DNA repair-deficient mutant RS321 of
Saccharomyces cerevisiae. The structural elucidation of the new compounds was performed by ES–MS and by 1D and 2D NMR spectroscopic methods.</description><identifier>ISSN: 0031-9422</identifier><identifier>EISSN: 1873-3700</identifier><identifier>DOI: 10.1016/S0031-9422(99)00105-3</identifier><identifier>PMID: 10389274</identifier><language>eng</language><publisher>Amsterdam: Elsevier Ltd</publisher><subject>Biological and medical sciences ; chemical constituents of plants ; Chemical constitution ; chemical structure ; Chioccoca alba ; DNA repair ; Fundamental and applied biological sciences. Psychology ; General pharmacology ; glucosides ; Glucosides - chemistry ; Glucosides - isolation & purification ; Glucosides - pharmacology ; Iridoid glucosides ; Iridoids ; Medical sciences ; medicinal plants ; medicinal properties ; Microbial Sensitivity Tests ; Molecular Structure ; mutants ; nuclear magnetic resonance spectroscopy ; Pharmacognosy. Homeopathy. Health food ; Pharmacology. Drug treatments ; Plant physiology and development ; Pyrans - chemistry ; Pyrans - isolation & purification ; Pyrans - pharmacology ; roots ; Rubiaceae ; Rubiaceae - chemistry ; Saccharomyces cerevisiae ; Saccharomyces cerevisiae - drug effects ; Seco-iridoid glucoside ; spectral analysis ; Spectrum Analysis</subject><ispartof>Phytochemistry (Oxford), 1999-07, Vol.51 (6), p.781-785</ispartof><rights>1999 Elsevier Science Ltd</rights><rights>1999 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c414t-21f40e3c812d05c4f2ac233e53650f5c341b1e23d6b79899c0b314b37ab4b3ec3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0031942299001053$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1844085$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10389274$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Carbonezi, Carlos Alberto</creatorcontrib><creatorcontrib>Martins, Dirceu</creatorcontrib><creatorcontrib>Young, Maria Claudia M</creatorcontrib><creatorcontrib>Lopes, Marcia N</creatorcontrib><creatorcontrib>Furlan, Maysa</creatorcontrib><creatorcontrib>Rodrigues Filho, Edson</creatorcontrib><creatorcontrib>Bolzani, Vanderlan da S</creatorcontrib><title>Iridoid and seco-iridoid glucosides from Chioccoca alba (Rubiaceae)</title><title>Phytochemistry (Oxford)</title><addtitle>Phytochemistry</addtitle><description>Phytochemical investigation of
Chioccoca alba afforded three new iridoids, alboside I, alboside II and alboside III, and a new
seco-iridoid alboside V. Alboside
IV showed moderate activity towards the DNA repair-deficient mutant RS321 of
Saccharomyces cerevisiae. The structural elucidation of the new compounds was performed by ES–MS and by 1D and 2D NMR spectroscopic methods.</description><subject>Biological and medical sciences</subject><subject>chemical constituents of plants</subject><subject>Chemical constitution</subject><subject>chemical structure</subject><subject>Chioccoca alba</subject><subject>DNA repair</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>General pharmacology</subject><subject>glucosides</subject><subject>Glucosides - chemistry</subject><subject>Glucosides - isolation & purification</subject><subject>Glucosides - pharmacology</subject><subject>Iridoid glucosides</subject><subject>Iridoids</subject><subject>Medical sciences</subject><subject>medicinal plants</subject><subject>medicinal properties</subject><subject>Microbial Sensitivity Tests</subject><subject>Molecular Structure</subject><subject>mutants</subject><subject>nuclear magnetic resonance spectroscopy</subject><subject>Pharmacognosy. Homeopathy. Health food</subject><subject>Pharmacology. 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Psychology</topic><topic>General pharmacology</topic><topic>glucosides</topic><topic>Glucosides - chemistry</topic><topic>Glucosides - isolation & purification</topic><topic>Glucosides - pharmacology</topic><topic>Iridoid glucosides</topic><topic>Iridoids</topic><topic>Medical sciences</topic><topic>medicinal plants</topic><topic>medicinal properties</topic><topic>Microbial Sensitivity Tests</topic><topic>Molecular Structure</topic><topic>mutants</topic><topic>nuclear magnetic resonance spectroscopy</topic><topic>Pharmacognosy. Homeopathy. Health food</topic><topic>Pharmacology. 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Chioccoca alba afforded three new iridoids, alboside I, alboside II and alboside III, and a new
seco-iridoid alboside V. Alboside
IV showed moderate activity towards the DNA repair-deficient mutant RS321 of
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| fulltext | fulltext |
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| ispartof | Phytochemistry (Oxford), 1999-07, Vol.51 (6), p.781-785 |
| issn | 0031-9422 1873-3700 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Biological and medical sciences chemical constituents of plants Chemical constitution chemical structure Chioccoca alba DNA repair Fundamental and applied biological sciences. Psychology General pharmacology glucosides Glucosides - chemistry Glucosides - isolation & purification Glucosides - pharmacology Iridoid glucosides Iridoids Medical sciences medicinal plants medicinal properties Microbial Sensitivity Tests Molecular Structure mutants nuclear magnetic resonance spectroscopy Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Plant physiology and development Pyrans - chemistry Pyrans - isolation & purification Pyrans - pharmacology roots Rubiaceae Rubiaceae - chemistry Saccharomyces cerevisiae Saccharomyces cerevisiae - drug effects Seco-iridoid glucoside spectral analysis Spectrum Analysis |
| title | Iridoid and seco-iridoid glucosides from Chioccoca alba (Rubiaceae) |
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