Iridoid and seco-iridoid glucosides from Chioccoca alba (Rubiaceae)

Phytochemical investigation of Chioccoca alba afforded three new iridoids, alboside I, alboside II and alboside III, and a new seco-iridoid alboside V. Alboside IV showed moderate activity towards the DNA repair-deficient mutant RS321 of Saccharomyces cerevisiae. The structural elucidation of the ne...

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Veröffentlicht in:	Phytochemistry (Oxford) 1999-07, Vol.51 (6), p.781-785
Hauptverfasser:	Carbonezi, Carlos Alberto, Martins, Dirceu, Young, Maria Claudia M, Lopes, Marcia N, Furlan, Maysa, Rodrigues Filho, Edson, Bolzani, Vanderlan da S
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences chemical constituents of plants Chemical constitution chemical structure Chioccoca alba DNA repair Fundamental and applied biological sciences. Psychology General pharmacology glucosides Glucosides - chemistry Glucosides - isolation & purification Glucosides - pharmacology Iridoid glucosides Iridoids Medical sciences medicinal plants medicinal properties Microbial Sensitivity Tests Molecular Structure mutants nuclear magnetic resonance spectroscopy Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Plant physiology and development Pyrans - chemistry Pyrans - isolation & purification Pyrans - pharmacology roots Rubiaceae Rubiaceae - chemistry Saccharomyces cerevisiae Saccharomyces cerevisiae - drug effects Seco-iridoid glucoside spectral analysis Spectrum Analysis
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Zusammenfassung:	Phytochemical investigation of Chioccoca alba afforded three new iridoids, alboside I, alboside II and alboside III, and a new seco-iridoid alboside V. Alboside IV showed moderate activity towards the DNA repair-deficient mutant RS321 of Saccharomyces cerevisiae. The structural elucidation of the new compounds was performed by ES–MS and by 1D and 2D NMR spectroscopic methods.
ISSN:	0031-9422 1873-3700
DOI:	10.1016/S0031-9422(99)00105-3