Embryonic Stem Cell Biology
ES cell research represents an exploding field of exploration. Initially predicted to provide rapid cures for numerous human diseases, the clinical usefulness of ES cell-derived cells remains untested in humans. However, ES cells have rapidly expanded our knowledge of human development and the molec...
Gespeichert in:
| Veröffentlicht in: | Advances in pediatrics 2008, Vol.55 (1), p.43-77 |
|---|---|
| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 77 |
|---|---|
| container_issue | 1 |
| container_start_page | 43 |
| container_title | Advances in pediatrics |
| container_volume | 55 |
| creator | Fritsch, Michael K., MD, PhD Singer, Don B., MD |
| description | ES cell research represents an exploding field of exploration. Initially predicted to provide rapid cures for numerous human diseases, the clinical usefulness of ES cell-derived cells remains untested in humans. However, ES cells have rapidly expanded our knowledge of human development and the molecular details of differentiation. Our ability to generate relatively pure populations of specifically differentiated cells for transplantation has markedly improved. It is hoped that soon researchers will overcome the biologic impediments to successful treatment of human disease with ES cell-derived cells. |
| doi_str_mv | 10.1016/j.yapd.2008.07.006 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_69858491</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0065310108000078</els_id><sourcerecordid>35883066</sourcerecordid><originalsourceid>FETCH-LOGICAL-c355t-5bc3dba98200ea8d4f7c03d46c2c55f9ee8961e08406d19218a8263ed40973853</originalsourceid><addsrcrecordid>eNqFkU1LAzEQhoMotn78AQXpyduuk80mOwsiaKkfIHionsM2mUrqbrcmrbD_3iwtCB40l4HwvC_DM4ydcUg5cHW1SLtqZdMMAFMoUgC1x4YcC0x4mal9Now_MhGRHbCjEBYAQijkh2zAS8ixyIohO580M9-1S2dG0zU1ozHV9ejOtXX73p2wg3lVBzrdzWP2dj95HT8mzy8PT-Pb58QIKdeJnBlhZ1WJcRGq0ObzwoCwuTKZkXJeEmGpOAHmoGzcjGOFmRJkcygLgVIcs8tt78q3nxsKa924YOIi1ZLaTdCqRIl5yf8FhUQUoFQEsy1ofBuCp7leeddUvtMcdO9OL3TvTvfuNBQ6moqhi137ZtaQ_YnsZEXgegtQlPHlyOtgHC0NWefJrLVt3d_9N7_ipnZRfFV_UEdh0W78MmrWXIdMg5721-uPBwjxFSi-AcFxkaY</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>35883066</pqid></control><display><type>article</type><title>Embryonic Stem Cell Biology</title><source>MEDLINE</source><source>Access via ScienceDirect (Elsevier)</source><creator>Fritsch, Michael K., MD, PhD ; Singer, Don B., MD</creator><creatorcontrib>Fritsch, Michael K., MD, PhD ; Singer, Don B., MD</creatorcontrib><description>ES cell research represents an exploding field of exploration. Initially predicted to provide rapid cures for numerous human diseases, the clinical usefulness of ES cell-derived cells remains untested in humans. However, ES cells have rapidly expanded our knowledge of human development and the molecular details of differentiation. Our ability to generate relatively pure populations of specifically differentiated cells for transplantation has markedly improved. It is hoped that soon researchers will overcome the biologic impediments to successful treatment of human disease with ES cell-derived cells.</description><identifier>ISSN: 0065-3101</identifier><identifier>EISSN: 1878-1926</identifier><identifier>DOI: 10.1016/j.yapd.2008.07.006</identifier><identifier>PMID: 19048727</identifier><language>eng</language><publisher>United States: Mosby, Inc</publisher><subject>Cardiovascular Diseases - therapy ; Cell Differentiation ; Central Nervous System Diseases - therapy ; Diabetes Mellitus - therapy ; Embryonic Stem Cells - physiology ; Epigenesis, Genetic ; Gastrointestinal Diseases - therapy ; Hematologic Diseases - therapy ; Humans ; Internal Medicine ; Membrane Proteins - physiology ; Pediatrics ; Signal Transduction ; Stem Cell Transplantation ; Transcription Factors - physiology</subject><ispartof>Advances in pediatrics, 2008, Vol.55 (1), p.43-77</ispartof><rights>Elsevier Inc.</rights><rights>2008 Elsevier Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c355t-5bc3dba98200ea8d4f7c03d46c2c55f9ee8961e08406d19218a8263ed40973853</citedby><cites>FETCH-LOGICAL-c355t-5bc3dba98200ea8d4f7c03d46c2c55f9ee8961e08406d19218a8263ed40973853</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.yapd.2008.07.006$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>315,781,785,3551,4025,27928,27929,27930,46000</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19048727$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Fritsch, Michael K., MD, PhD</creatorcontrib><creatorcontrib>Singer, Don B., MD</creatorcontrib><title>Embryonic Stem Cell Biology</title><title>Advances in pediatrics</title><addtitle>Adv Pediatr</addtitle><description>ES cell research represents an exploding field of exploration. Initially predicted to provide rapid cures for numerous human diseases, the clinical usefulness of ES cell-derived cells remains untested in humans. However, ES cells have rapidly expanded our knowledge of human development and the molecular details of differentiation. Our ability to generate relatively pure populations of specifically differentiated cells for transplantation has markedly improved. It is hoped that soon researchers will overcome the biologic impediments to successful treatment of human disease with ES cell-derived cells.</description><subject>Cardiovascular Diseases - therapy</subject><subject>Cell Differentiation</subject><subject>Central Nervous System Diseases - therapy</subject><subject>Diabetes Mellitus - therapy</subject><subject>Embryonic Stem Cells - physiology</subject><subject>Epigenesis, Genetic</subject><subject>Gastrointestinal Diseases - therapy</subject><subject>Hematologic Diseases - therapy</subject><subject>Humans</subject><subject>Internal Medicine</subject><subject>Membrane Proteins - physiology</subject><subject>Pediatrics</subject><subject>Signal Transduction</subject><subject>Stem Cell Transplantation</subject><subject>Transcription Factors - physiology</subject><issn>0065-3101</issn><issn>1878-1926</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkU1LAzEQhoMotn78AQXpyduuk80mOwsiaKkfIHionsM2mUrqbrcmrbD_3iwtCB40l4HwvC_DM4ydcUg5cHW1SLtqZdMMAFMoUgC1x4YcC0x4mal9Now_MhGRHbCjEBYAQijkh2zAS8ixyIohO580M9-1S2dG0zU1ozHV9ejOtXX73p2wg3lVBzrdzWP2dj95HT8mzy8PT-Pb58QIKdeJnBlhZ1WJcRGq0ObzwoCwuTKZkXJeEmGpOAHmoGzcjGOFmRJkcygLgVIcs8tt78q3nxsKa924YOIi1ZLaTdCqRIl5yf8FhUQUoFQEsy1ofBuCp7leeddUvtMcdO9OL3TvTvfuNBQ6moqhi137ZtaQ_YnsZEXgegtQlPHlyOtgHC0NWefJrLVt3d_9N7_ipnZRfFV_UEdh0W78MmrWXIdMg5721-uPBwjxFSi-AcFxkaY</recordid><startdate>2008</startdate><enddate>2008</enddate><creator>Fritsch, Michael K., MD, PhD</creator><creator>Singer, Don B., MD</creator><general>Mosby, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7U5</scope><scope>8FD</scope><scope>L7M</scope><scope>7X8</scope></search><sort><creationdate>2008</creationdate><title>Embryonic Stem Cell Biology</title><author>Fritsch, Michael K., MD, PhD ; Singer, Don B., MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c355t-5bc3dba98200ea8d4f7c03d46c2c55f9ee8961e08406d19218a8263ed40973853</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Cardiovascular Diseases - therapy</topic><topic>Cell Differentiation</topic><topic>Central Nervous System Diseases - therapy</topic><topic>Diabetes Mellitus - therapy</topic><topic>Embryonic Stem Cells - physiology</topic><topic>Epigenesis, Genetic</topic><topic>Gastrointestinal Diseases - therapy</topic><topic>Hematologic Diseases - therapy</topic><topic>Humans</topic><topic>Internal Medicine</topic><topic>Membrane Proteins - physiology</topic><topic>Pediatrics</topic><topic>Signal Transduction</topic><topic>Stem Cell Transplantation</topic><topic>Transcription Factors - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Fritsch, Michael K., MD, PhD</creatorcontrib><creatorcontrib>Singer, Don B., MD</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>Technology Research Database</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>MEDLINE - Academic</collection><jtitle>Advances in pediatrics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Fritsch, Michael K., MD, PhD</au><au>Singer, Don B., MD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Embryonic Stem Cell Biology</atitle><jtitle>Advances in pediatrics</jtitle><addtitle>Adv Pediatr</addtitle><date>2008</date><risdate>2008</risdate><volume>55</volume><issue>1</issue><spage>43</spage><epage>77</epage><pages>43-77</pages><issn>0065-3101</issn><eissn>1878-1926</eissn><abstract>ES cell research represents an exploding field of exploration. Initially predicted to provide rapid cures for numerous human diseases, the clinical usefulness of ES cell-derived cells remains untested in humans. However, ES cells have rapidly expanded our knowledge of human development and the molecular details of differentiation. Our ability to generate relatively pure populations of specifically differentiated cells for transplantation has markedly improved. It is hoped that soon researchers will overcome the biologic impediments to successful treatment of human disease with ES cell-derived cells.</abstract><cop>United States</cop><pub>Mosby, Inc</pub><pmid>19048727</pmid><doi>10.1016/j.yapd.2008.07.006</doi><tpages>35</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0065-3101 |
| ispartof | Advances in pediatrics, 2008, Vol.55 (1), p.43-77 |
| issn | 0065-3101 1878-1926 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_69858491 |
| source | MEDLINE; Access via ScienceDirect (Elsevier) |
| subjects | Cardiovascular Diseases - therapy Cell Differentiation Central Nervous System Diseases - therapy Diabetes Mellitus - therapy Embryonic Stem Cells - physiology Epigenesis, Genetic Gastrointestinal Diseases - therapy Hematologic Diseases - therapy Humans Internal Medicine Membrane Proteins - physiology Pediatrics Signal Transduction Stem Cell Transplantation Transcription Factors - physiology |
| title | Embryonic Stem Cell Biology |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-11T19%3A10%3A29IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Embryonic%20Stem%20Cell%20Biology&rft.jtitle=Advances%20in%20pediatrics&rft.au=Fritsch,%20Michael%20K.,%20MD,%20PhD&rft.date=2008&rft.volume=55&rft.issue=1&rft.spage=43&rft.epage=77&rft.pages=43-77&rft.issn=0065-3101&rft.eissn=1878-1926&rft_id=info:doi/10.1016/j.yapd.2008.07.006&rft_dat=%3Cproquest_cross%3E35883066%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=35883066&rft_id=info:pmid/19048727&rft_els_id=S0065310108000078&rfr_iscdi=true |