Embryonic Stem Cell Biology

ES cell research represents an exploding field of exploration. Initially predicted to provide rapid cures for numerous human diseases, the clinical usefulness of ES cell-derived cells remains untested in humans. However, ES cells have rapidly expanded our knowledge of human development and the molec...

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Veröffentlicht in:	Advances in pediatrics 2008, Vol.55 (1), p.43-77
Hauptverfasser:	Fritsch, Michael K., MD, PhD, Singer, Don B., MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Cardiovascular Diseases - therapy Cell Differentiation Central Nervous System Diseases - therapy Diabetes Mellitus - therapy Embryonic Stem Cells - physiology Epigenesis, Genetic Gastrointestinal Diseases - therapy Hematologic Diseases - therapy Humans Internal Medicine Membrane Proteins - physiology Pediatrics Signal Transduction Stem Cell Transplantation Transcription Factors - physiology
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Beschreibung
Zusammenfassung:	ES cell research represents an exploding field of exploration. Initially predicted to provide rapid cures for numerous human diseases, the clinical usefulness of ES cell-derived cells remains untested in humans. However, ES cells have rapidly expanded our knowledge of human development and the molecular details of differentiation. Our ability to generate relatively pure populations of specifically differentiated cells for transplantation has markedly improved. It is hoped that soon researchers will overcome the biologic impediments to successful treatment of human disease with ES cell-derived cells.
ISSN:	0065-3101 1878-1926
DOI:	10.1016/j.yapd.2008.07.006