Fear of Recurrence, Symptom Burden, and Health-Related Quality of Life in Men With Prostate Cancer

Objectives To examine the contributions of fear of recurrence and the more commonly examined treatment-related symptoms to the health-related quality of life (HRQOL) of men treated for localized prostate cancer. Methods A total of 730 men with localized disease were identified from the Cancer of the...

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Veröffentlicht in:	Urology (Ridgewood, N.J.) N.J.), 2008-12, Vol.72 (6), p.1269-1273
Hauptverfasser:	Bellizzi, Keith M, Latini, David M, Cowan, Janet E, DuChane, Janeen, Carroll, Peter R
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Biological and medical sciences Brachytherapy - methods Comorbidity Fear Gynecology. Andrology. Obstetrics Humans Male Male genital diseases Medical sciences Middle Aged Nephrology. Urinary tract diseases Patient Education as Topic Prostatectomy - psychology Prostatic Neoplasms - pathology Prostatic Neoplasms - psychology Prostatic Neoplasms - radiotherapy Prostatic Neoplasms - surgery Quality of Life - psychology Radiotherapy - methods Recurrence Regression Analysis Treatment Outcome Tumors Tumors of the urinary system Urinary tract. Prostate gland Urology
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Zusammenfassung:	Objectives To examine the contributions of fear of recurrence and the more commonly examined treatment-related symptoms to the health-related quality of life (HRQOL) of men treated for localized prostate cancer. Methods A total of 730 men with localized disease were identified from the Cancer of the Prostate Strategic Urologic Research Endeavor, a national, prospective study of men with prostate cancer. Pre- to post-treatment changes in fear of recurrence, treatment-specific symptoms and burden, comorbidities at diagnosis, number of new symptoms, and post-treatment HRQOL data were analyzed. Results Linear regression, adjusted for clinical and demographic characteristics, showed that improved fear of recurrence ( P
ISSN:	0090-4295 1527-9995
DOI:	10.1016/j.urology.2007.12.084