Clear differences in adiponectin level and glutathione redox status revealed in obese and normal-weight patients with psoriasis

Summary Background Several studies have shown increased prevalence of obesity in patients with psoriasis. Objectives To characterize both inflammatory‐ and oxidative stress‐related differences between obese patients with psoriasis (OPP) and normal‐weight patients with psoriasis (NWPP). Methods The plasma concentrations of adiponectin and interleukin (IL)‐6 were analysed by quantitative sandwich enzyme immunoassay technique in 10 patients with a body mass index (BMI) 30. Total glutathione and oxidized glutathione levels were measured spectrophotometrically. Results Plasma concentration of adiponectin in NWPP was more than twice the level in healthy normal‐weight controls (P