Effect of Peumus boldus on the labeling of red blood cells and plasma proteins with Technetium-99m

Peumus boldus is used in popular medicine in Brazil. The influence of Peumus boldus on the labeling of red blood cells and plasma proteins with 99mTc was studied. Stannous chloride and 99mTc pertechnetate were incubated with blood and a tincture of Peumus boldus. Aliquots of plasma and blood cells w...

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Veröffentlicht in:Applied radiation and isotopes 1999-08, Vol.51 (2), p.145-149
Hauptverfasser: Wancke Reiniger, Ingrid, Fonseca de Oliveira, Joelma, Caldeira-de-Araújo, Adriano, Bernardo-Filho, Mario
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container_end_page 149
container_issue 2
container_start_page 145
container_title Applied radiation and isotopes
container_volume 51
creator Wancke Reiniger, Ingrid
Fonseca de Oliveira, Joelma
Caldeira-de-Araújo, Adriano
Bernardo-Filho, Mario
description Peumus boldus is used in popular medicine in Brazil. The influence of Peumus boldus on the labeling of red blood cells and plasma proteins with 99mTc was studied. Stannous chloride and 99mTc pertechnetate were incubated with blood and a tincture of Peumus boldus. Aliquots of plasma and blood cells were isolated from the mixture and treated with trichloroacetic acid (TCA). After separation, analysis of the soluble and insoluble fractions showed a rapid uptake of the radioactivity by blood cells in the presence of the drug, whereas there was a slight decrease in the amount of 99mTc radioactivity in the TCA-insoluble fraction of plasma.
doi_str_mv 10.1016/S0969-8043(98)00200-0
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subjects Animals
Anti-oxidant activity
Antioxidants
Blood
Blood Proteins - metabolism
Cells
Drug products
Erythrocytes - metabolism
Isotope Labeling - methods
Medicine, Traditional
Peumus boldus
Plant Extracts - pharmacology
Plasma proteins
Proteins
Radioactivity
Radiopharmaceuticals - metabolism
Rats
Rats, Wistar
Red blood cells
Separation
Sodium Pertechnetate Tc 99m - blood
Solubility
Technetium
Technetium - blood
Technetium-99m
title Effect of Peumus boldus on the labeling of red blood cells and plasma proteins with Technetium-99m
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