Regression of vasomotor disorders under intrathecal baclofen in a case of spastic paraplegia

Regression of vasomotor disorders under intrathecal baclofen in a case of spastic paraplegia

Continuous intrathecal baclofen infusion via a subcutaneously implanted programmable pump has been used in the treatment of severe spasticity. Improvement classically concerns the neurological (hypertonia, spasms, hyperreflexia), urological (bladder function) and other clinically relevant outcomes,...

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Veröffentlicht in:Spinal cord 1999-05, Vol.37 (5), p.370-372
Hauptverfasser: Rode, G, Mertens, P, Beneton, C, Schmitt, M, Boisson, D
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Anatomy
Baclofen - administration & dosage
Baclofen - therapeutic use
Biological and medical sciences
Biomedical and Life Sciences
Biomedicine
case-report
Disability Evaluation
Gabaergic and benzodiazepinic system
Human Physiology
Humans
Infusion Pumps, Implantable
Male
Medical sciences
Motor Skills - drug effects
Muscle Relaxants, Central - administration & dosage
Muscle Relaxants, Central - therapeutic use
Muscle Spasticity - drug therapy
Muscle Spasticity - etiology
Muscle Spasticity - physiopathology
Neurochemistry
Neuropharmacology
Neuropsychology
Neurosciences
Neurotransmitters. Neurotransmission. Receptors
Paraplegia - etiology
Paraplegia - physiopathology
Pharmacology. Drug treatments
Spinal Fractures - complications
Urinary Bladder, Neurogenic - physiopathology
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Beschreibung
Zusammenfassung:Continuous intrathecal baclofen infusion via a subcutaneously implanted programmable pump has been used in the treatment of severe spasticity. Improvement classically concerns the neurological (hypertonia, spasms, hyperreflexia), urological (bladder function) and other clinically relevant outcomes, such as functional status of daily living. This short note reports on another effect of intrathecal baclofen on vasomotor disorders and cyanosis in the lower limbs, described in a patient with spastic paraplegia.
ISSN:1362-4393
1476-5624
DOI:10.1038/sj.sc.3100838