Idiopathic thrombocytopenia after cytomegalovirus infection in a renal transplant recipient
Infection with cytomegalovirus (CMV) is a frequent complication of organ transplantation and presents a spectrum of disease ranging from asymptomatic viremia to life-threatening tissue-invasive disease. CMV is also lymphotrophic, with the potential to induce autoimmune disease, although immunosuppre...
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| Veröffentlicht in: | American journal of kidney diseases 1999-06, Vol.33 (6), p.E22-E24 |
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| container_issue | 6 |
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| container_title | American journal of kidney diseases |
| container_volume | 33 |
| creator | McLaughlin, Kevin Cruickshank, Moira Hollomby, David Jevnikar, Anthony Muirhead, Norman |
| description | Infection with cytomegalovirus (CMV) is a frequent complication of organ transplantation and presents a spectrum of disease ranging from asymptomatic viremia to life-threatening tissue-invasive disease. CMV is also lymphotrophic, with the potential to induce autoimmune disease, although immunosuppressive therapy may prevent or attenuate the clinical course in transplant patients. We report a case of idiopathic thrombocytopenic purpura occurring in a renal transplant recipient after primary CMV infection and discuss the possible mechanisms involved. |
| doi_str_mv | 10.1016/S0272-6386(99)70173-3 |
| format | Article |
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CMV is also lymphotrophic, with the potential to induce autoimmune disease, although immunosuppressive therapy may prevent or attenuate the clinical course in transplant patients. We report a case of idiopathic thrombocytopenic purpura occurring in a renal transplant recipient after primary CMV infection and discuss the possible mechanisms involved.</description><identifier>ISSN: 0272-6386</identifier><identifier>EISSN: 1523-6838</identifier><identifier>DOI: 10.1016/S0272-6386(99)70173-3</identifier><identifier>PMID: 10352222</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Cytomegalovirus ; Cytomegalovirus Infections - complications ; Humans ; idiopathic thrombocytopenic purpura ; Kidney Transplantation ; Male ; Middle Aged ; Purpura, Thrombocytopenic, Idiopathic - etiology ; renal transplantation</subject><ispartof>American journal of kidney diseases, 1999-06, Vol.33 (6), p.E22-E24</ispartof><rights>1999 National Kidney Foundation, Inc</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c427t-16a840d192e57860c499791a3b544860c2ed30d0505a219533f38033ede9ff633</citedby><cites>FETCH-LOGICAL-c427t-16a840d192e57860c499791a3b544860c2ed30d0505a219533f38033ede9ff633</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/S0272-6386(99)70173-3$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,777,781,3537,27905,27906,45976</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10352222$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>McLaughlin, Kevin</creatorcontrib><creatorcontrib>Cruickshank, Moira</creatorcontrib><creatorcontrib>Hollomby, David</creatorcontrib><creatorcontrib>Jevnikar, Anthony</creatorcontrib><creatorcontrib>Muirhead, Norman</creatorcontrib><title>Idiopathic thrombocytopenia after cytomegalovirus infection in a renal transplant recipient</title><title>American journal of kidney diseases</title><addtitle>Am J Kidney Dis</addtitle><description>Infection with cytomegalovirus (CMV) is a frequent complication of organ transplantation and presents a spectrum of disease ranging from asymptomatic viremia to life-threatening tissue-invasive disease. CMV is also lymphotrophic, with the potential to induce autoimmune disease, although immunosuppressive therapy may prevent or attenuate the clinical course in transplant patients. We report a case of idiopathic thrombocytopenic purpura occurring in a renal transplant recipient after primary CMV infection and discuss the possible mechanisms involved.</description><subject>Cytomegalovirus</subject><subject>Cytomegalovirus Infections - complications</subject><subject>Humans</subject><subject>idiopathic thrombocytopenic purpura</subject><subject>Kidney Transplantation</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Purpura, Thrombocytopenic, Idiopathic - etiology</subject><subject>renal transplantation</subject><issn>0272-6386</issn><issn>1523-6838</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1999</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1PxCAQhonR6Lr6EzQ9GT1UoVNoORlj_Eo28aCePBCWThXTlgqsif9e6hrjTS7DTB544SHkgNFTRpk4e6BFVeQCanEs5UlFWQU5bJAZ4wXkooZ6k8x-kR2yG8IbpVSCENtkh1HgRVoz8nzXWDfq-GpNFl-965fOfEY34mB1ptuIPpv6Hl905z6sX4XMDi2aaN2QdpnOPA66y6LXQxg7PcQ0MHa0OMQ9stXqLuD-T52Tp-urx8vbfHF_c3d5schNWVQxZ0LXJW2YLJBXtaCmlLKSTMOSl-XUF9gAbSinXBdMcoAWagqADcq2FQBzcrS-d_TufYUhqt4Gg116DbpVUELWtObAEsjXoPEuBI-tGr3ttf9UjKrJqvq2qiZlSkr1bVVNAYc_Aatlj82fU2uNCThfA5i--WHRq2CSAYONTTaiapz9J-ILPL2HuQ</recordid><startdate>19990601</startdate><enddate>19990601</enddate><creator>McLaughlin, Kevin</creator><creator>Cruickshank, Moira</creator><creator>Hollomby, David</creator><creator>Jevnikar, Anthony</creator><creator>Muirhead, Norman</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19990601</creationdate><title>Idiopathic thrombocytopenia after cytomegalovirus infection in a renal transplant recipient</title><author>McLaughlin, Kevin ; Cruickshank, Moira ; Hollomby, David ; Jevnikar, Anthony ; Muirhead, Norman</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c427t-16a840d192e57860c499791a3b544860c2ed30d0505a219533f38033ede9ff633</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1999</creationdate><topic>Cytomegalovirus</topic><topic>Cytomegalovirus Infections - complications</topic><topic>Humans</topic><topic>idiopathic thrombocytopenic purpura</topic><topic>Kidney Transplantation</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Purpura, Thrombocytopenic, Idiopathic - etiology</topic><topic>renal transplantation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>McLaughlin, Kevin</creatorcontrib><creatorcontrib>Cruickshank, Moira</creatorcontrib><creatorcontrib>Hollomby, David</creatorcontrib><creatorcontrib>Jevnikar, Anthony</creatorcontrib><creatorcontrib>Muirhead, Norman</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>American journal of kidney diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>McLaughlin, Kevin</au><au>Cruickshank, Moira</au><au>Hollomby, David</au><au>Jevnikar, Anthony</au><au>Muirhead, Norman</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Idiopathic thrombocytopenia after cytomegalovirus infection in a renal transplant recipient</atitle><jtitle>American journal of kidney diseases</jtitle><addtitle>Am J Kidney Dis</addtitle><date>1999-06-01</date><risdate>1999</risdate><volume>33</volume><issue>6</issue><spage>E22</spage><epage>E24</epage><pages>E22-E24</pages><issn>0272-6386</issn><eissn>1523-6838</eissn><abstract>Infection with cytomegalovirus (CMV) is a frequent complication of organ transplantation and presents a spectrum of disease ranging from asymptomatic viremia to life-threatening tissue-invasive disease. CMV is also lymphotrophic, with the potential to induce autoimmune disease, although immunosuppressive therapy may prevent or attenuate the clinical course in transplant patients. We report a case of idiopathic thrombocytopenic purpura occurring in a renal transplant recipient after primary CMV infection and discuss the possible mechanisms involved.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>10352222</pmid><doi>10.1016/S0272-6386(99)70173-3</doi></addata></record> |
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| identifier | ISSN: 0272-6386 |
| ispartof | American journal of kidney diseases, 1999-06, Vol.33 (6), p.E22-E24 |
| issn | 0272-6386 1523-6838 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Cytomegalovirus Cytomegalovirus Infections - complications Humans idiopathic thrombocytopenic purpura Kidney Transplantation Male Middle Aged Purpura, Thrombocytopenic, Idiopathic - etiology renal transplantation |
| title | Idiopathic thrombocytopenia after cytomegalovirus infection in a renal transplant recipient |
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