Idiopathic thrombocytopenia after cytomegalovirus infection in a renal transplant recipient

Infection with cytomegalovirus (CMV) is a frequent complication of organ transplantation and presents a spectrum of disease ranging from asymptomatic viremia to life-threatening tissue-invasive disease. CMV is also lymphotrophic, with the potential to induce autoimmune disease, although immunosuppre...

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Veröffentlicht in:American journal of kidney diseases 1999-06, Vol.33 (6), p.E22-E24
Hauptverfasser: McLaughlin, Kevin, Cruickshank, Moira, Hollomby, David, Jevnikar, Anthony, Muirhead, Norman
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Sprache:eng
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Zusammenfassung:Infection with cytomegalovirus (CMV) is a frequent complication of organ transplantation and presents a spectrum of disease ranging from asymptomatic viremia to life-threatening tissue-invasive disease. CMV is also lymphotrophic, with the potential to induce autoimmune disease, although immunosuppressive therapy may prevent or attenuate the clinical course in transplant patients. We report a case of idiopathic thrombocytopenic purpura occurring in a renal transplant recipient after primary CMV infection and discuss the possible mechanisms involved.
ISSN:0272-6386
1523-6838
DOI:10.1016/S0272-6386(99)70173-3