The correlation of thrombolysis in myocardial infarction frame count with insulin resistance in patients with slow coronary flow

BACKGROUNDIt has been reported that coronary endothelial dysfunction plays an important pathogenetic role in patients with slow coronary flow (SCF). Insulin resistance is defined as impairment of insulin-stimulated glucose and/or lipid metabolism, while endothelial dysfunction is defined as paradoxical or inadequate endothelial-mediated vasodilation. In this study, we aimed to evaluate insulin resistance in patients with SCF. METHODSThe study population included 25 patients with SCF and 28 healthy controls. Insulin resistance was estimated via homeostasis model assessment insulin resistance index (HOMA-IR). RESULTSPatients with SCF had higher high-sensitive C-reactive protein (hs-CRP) and HOMA-IR scores (P