Embryonic delay in growth and development related to confined placental trisomy 16 mosaicism, diagnosed by I-Space Virtual Reality

Objective To demonstrate the use of a novel three-dimensional (3D) virtual reality (VR) system in the visualization of first trimester growth and development in a case of confined placental trisomy 16 mosaicism (CPM+16). Design Case report. Setting Prospective study on first trimester growth using a...

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Veröffentlicht in:	Fertility and sterility 2008-11, Vol.90 (5), p.2017.e19-2017.e22
Hauptverfasser:	Verwoerd-Dikkeboom, Christine M., M.D, van Heesch, Peter N.A.C.M, Koning, Anton H.J., Ph.D, Galjaard, Robert-Jan H., M.D., Ph.D, Exalto, Niek, M.D., Ph.D, Steegers, Eric A.P., M.D., Ph.D
Format:	Artikel
Sprache:	eng
Schlagworte:	3D ultrasound Adult Amniocentesis Carnegie stages Chorionic Villi Sampling Chromosomes, Human, Pair 16 Confined placental mosaicism Female Fetal Growth Retardation - diagnostic imaging Fetal Growth Retardation - genetics Fetal Growth Retardation - metabolism Humans Image Interpretation, Computer-Assisted Imaging, Three-Dimensional Infant, Low Birth Weight Infant, Newborn Internal Medicine Live Birth Mosaicism Obstetrics and Gynecology Pregnancy Pregnancy Trimester, Third Pregnancy-Associated Plasma Protein-A - analysis Trisomy trisomy 16 Ultrasonography, Prenatal User-Computer Interface virtual reality
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Zusammenfassung:	Objective To demonstrate the use of a novel three-dimensional (3D) virtual reality (VR) system in the visualization of first trimester growth and development in a case of confined placental trisomy 16 mosaicism (CPM+16). Design Case report. Setting Prospective study on first trimester growth using a 3D VR system. Patient(s) A 34-year-old gravida 1, para 0 was seen weekly in the first trimester for 3D ultrasound examinations. Intervention(s) Chorionic villus sampling was performed because of an enlarged nuchal translucency (NT) measurement and low pregnancy-associated plasma protein-A levels, followed by amniocentesis. Result(s) Amniocentesis revealed a CPM+16. On two-dimensional (2D) and 3D ultrasound no structural anomalies were found with normal fetal Dopplers. Growth remained below the 2.3 percentile. At 37 weeks, a female child of 2010 g (
ISSN:	0015-0282 1556-5653
DOI:	10.1016/j.fertnstert.2008.07.1721