Human adult testis-derived pluripotent stem cells: revealing plasticity from the germline

A recent publication in Nature by Conrad et al. (2008) reports the generation of pluripotent stem cells from isolated human adult testicular germ cells. This work identifies a new source of stem cells for potential autologous therapeutic applications in men.

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Bibliographische Detailangaben
Veröffentlicht in:	Cell stem cell 2008-11, Vol.3 (5), p.471-472
Hauptverfasser:	Payne, Christopher J, Braun, Robert E
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Age Factors Animals Cell Differentiation - physiology Cell Lineage - physiology Cell Separation - methods Cellular Reprogramming - physiology DNA Methylation - physiology Humans Integrin alpha6 Leukemia Inhibitory Factor - metabolism Male Mice Pluripotent Stem Cells - cytology Pluripotent Stem Cells - metabolism Signal Transduction Spermatogonia - cytology Spermatogonia - metabolism Stem Cell Transplantation - methods Testis - cytology
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Beschreibung
Zusammenfassung:	A recent publication in Nature by Conrad et al. (2008) reports the generation of pluripotent stem cells from isolated human adult testicular germ cells. This work identifies a new source of stem cells for potential autologous therapeutic applications in men.
ISSN:	1934-5909 1875-9777
DOI:	10.1016/j.stem.2008.10.009