Efficacy of Brazilian propolis gel for the management of denture stomatitis: a pilot study
Denture stomatitis presents as a chronic disease in denture-bearing patients, especially under maxillary prosthesis. Despite the existence of a great number of antifungal agents, treatment failure is observed frequently. Propolis, a natural bee product, possesses well-documented antifungal and anti-...
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Veröffentlicht in: | Phytotherapy research 2008-11, Vol.22 (11), p.1544-1547 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Denture stomatitis presents as a chronic disease in denture-bearing patients, especially under maxillary prosthesis. Despite the existence of a great number of antifungal agents, treatment failure is observed frequently. Propolis, a natural bee product, possesses well-documented antifungal and anti-inflammatory activities. The purpose of this study was to evaluate the clinical efficacy of a new Brazilian propolis gel formulation in patients diagnosed with denture stomatitis. Thirty complete-denture wearers with denture stomatitis were enrolled in this pilot study. At baseline, clinical evaluation was performed by a single clinician and instructions for denture hygiene were provided. Fifteen patients received Daktarin® (Miconazole gel) and 15 received Brazilian propolis gel. All patients were recommended to apply the product four times a day during one week. Clinical evaluation was repeated by the same clinician after treatment. All patients treated with Brazilian propolis gel and Daktarin® had complete clinical remission of palatal edema and erythema. This new Brazilian propolis gel formulation had efficacy comparable to Daktarin® and could be an alternative topical choice for the treatment of denture stomatitis. Copyright © 2008 John Wiley & Sons, Ltd. |
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ISSN: | 0951-418X 1099-1573 |
DOI: | 10.1002/ptr.2541 |