Balance of adiponectin and leptin modulates breast cancer cell growth

There is lack of information concerning how the ratio of adiponectin to leptin in serum affects breast cancer (Brca) proliferation. It is possible that the link between obesity and increased risk for aggressive Brca is in part due to the milieu of cytokines synthesized and released by the adipose ti...

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Veröffentlicht in:Cell research 2008-11, Vol.18 (11), p.1154-1156
Hauptverfasser: Grossmann, Michael E, Ray, Amitabha, Dogan, Soner, Mizuno, Nancy K, Cleary, Margot P
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container_title Cell research
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creator Grossmann, Michael E
Ray, Amitabha
Dogan, Soner
Mizuno, Nancy K
Cleary, Margot P
description There is lack of information concerning how the ratio of adiponectin to leptin in serum affects breast cancer (Brca) proliferation. It is possible that the link between obesity and increased risk for aggressive Brca is in part due to the milieu of cytokines synthesized and released by the adipose tissue [1]. Adiponectin (also known as adipocyte complement-related protein of 30 kDa (Acrp30)) and leptin are two specific cytokines secreted by the adipose tissue.
doi_str_mv 10.1038/cr.2008.293
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It is possible that the link between obesity and increased risk for aggressive Brca is in part due to the milieu of cytokines synthesized and released by the adipose tissue [1]. 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source MEDLINE; Springer Nature - Complete Springer Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals
subjects Adiponectin - blood
Adiponectin - metabolism
Biomedical and Life Sciences
Breast cancer
Breast Neoplasms - metabolism
Cell Biology
Cell Line, Tumor
Cell Proliferation
Cells, Cultured
Female
Humans
Leptin - blood
Leptin - metabolism
letter-to-the-editor
Life Sciences
物理因素
生物学
癌细胞
title Balance of adiponectin and leptin modulates breast cancer cell growth
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