A randomized study of adefovir dipivoxil in place of HBIG in combination with lamivudine as post–liver transplantation hepatitis B prophylaxis

Prior to effective prophylaxis, liver transplantation for hepatitis B virus (HBV)‐related disease was frequently complicated by recurrence, which could be severe and rapidly progressive. Combination hepatitis B immunoglobulin (HBIG) and lamivudine prophylaxis reduces this rate of recurrence to

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Bibliographische Detailangaben
Veröffentlicht in:	Hepatology (Baltimore, Md.) Md.), 2008-11, Vol.48 (5), p.1460-1466
Hauptverfasser:	Angus, Peter W., Patterson, Scott J., Strasser, Simone I., McCaughan, Geoffrey W., Gane, Edward
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenine - analogs & derivatives Adenine - therapeutic use Adult Aged Antiviral Agents - therapeutic use Biological and medical sciences DNA, Viral - blood Female Gastroenterology. Liver. Pancreas. Abdomen Hepatitis B - immunology Hepatitis B - prevention & control Human viral diseases Humans Immunization, Passive Immunoglobulins - therapeutic use Infectious diseases Lamivudine - therapeutic use Liver Transplantation - adverse effects Liver, biliary tract, pancreas, portal circulation, spleen Liver. Biliary tract. Portal circulation. Exocrine pancreas Male Medical sciences Middle Aged Organophosphonates - therapeutic use Patient Selection Postoperative Complications - prevention & control Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the digestive system Viral diseases Viral hepatitis Viral Load
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Beschreibung
Zusammenfassung:	Prior to effective prophylaxis, liver transplantation for hepatitis B virus (HBV)‐related disease was frequently complicated by recurrence, which could be severe and rapidly progressive. Combination hepatitis B immunoglobulin (HBIG) and lamivudine prophylaxis reduces this rate of recurrence to
ISSN:	0270-9139 1527-3350
DOI:	10.1002/hep.22524