Prostanoids and Related Compounds. VII. Synthesis and Inhibitory Activity of 1-Isoindolinone Derivatives Possessing Inhibitory Activity against Thromboxane A2 Analog (U-46619)-Induced Vasoconstriction
We have synthesized a series of novel 1-isoindolinone derivatives, which inhibited the contraction of pig coronary artery induced by U-46619, a thromboxane A2 analog.
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Veröffentlicht in: | Chemical & pharmaceutical bulletin 1999/04/15, Vol.47(4), pp.529-535 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | We have synthesized a series of novel 1-isoindolinone derivatives, which inhibited the contraction of pig coronary artery induced by U-46619, a thromboxane A2 analog. |
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ISSN: | 0009-2363 1347-5223 |
DOI: | 10.1248/cpb.47.529 |